Cyclorphine

Cychlorphine is a synthetic opioid chemical compound which has been sold as a designer drug, reported in five European countries since 2024, and in the USA. It has been found in Canada as of September 2025. It is similar in chemical structure to known opioid agonists such as brorphine and spirochlorphine, and is claimed to be an opioid with similar or slightly higher potency than fentanyl, but no pharmacological data for cychlorphine has been published. It is not a structural analog of morphine, despite the similar name. Instead, it is an orphine.