EMPD

Extramammary Paget's disease (EMPD) is a rare and slow-growing cancer, which occurs within the epithelial tissues and accounts for 6.5% of all Paget's disease. This disease presents similarly to the more conventional form of mammary Paget's disease (MPD). However, unlike MPD, which occurs in large milk-carrying ducts in the breast and then extends into the epidermis, EMPD begins in glandular regions rich in apocrine secretions outside the mammary glands. EMPD incidence is increasing by 3.2% every year, affecting hormonally-targeted tissues such as the vulva and scrotum. In women, 81.3% of EMPD cases are related to the vulva, while for men, 43.2% of the manifestations present at the scrotum.